Text-to-speech technology incorporated into laboratory data collection devices has allowed B/VI students and professionals to perform hands-on experiments with real time data collection. Individuals with language based learning differences (dyslexia, dyscalculia, etc.) commonly use text-to-speech accommodations for their coursework. To date, the text-to-speech technology adapted for B/VI individuals has not been tested with individuals with language based learning differences. This presentation will showcase several examples of chemical experiments where the text-to-speech data collection has been utilized for students with language based learning differences. The presentation will also include a summary of feedback collected from students.