Course-Based Undergraduate Research Experiences (CUREs)can have significant impacts on student learning and professional skill development. CURE participants often show improvement in content knowledge, self-confidence/belongingin the field, and understanding of the scientific process. However, the impact of CUREs on non-traditional students, and particularly on students with disabilities, is not yet fully understood. CUREs were developed for Deaf and Hard-of Hearing (D/HH) chemistry students at Rochester Institute of Technology’s (RIT) National Technical Institute for the Deaf (NTID). The courses, students’ experiences, and accessibility aspects will be discussed. We hope that these early examples of accessible CUREs can be a model for future inclusive experiences for STEM students with disabilities.